Active suspension control of electric vehicle with in-wheel motors

In-wheel motor (IWM) technology has attracted increasing research interests in recent years due to the numerous advantages it offers. However, the direct attachment of IWMs to the wheels can result in an increase in the vehicle unsprung mass and a significant drop in the suspension ride comfort performance and road holding stability. Other issues such as motor bearing wear motor vibration, air-gap eccentricity and residual unbalanced radial force can adversely influence the motor vibration, passenger comfort and vehicle rollover stability. Active suspension and optimized passive suspension are possible methods deployed to improve the ride comfort and safety of electric vehicles equipped with inwheel motor. The trade-off between ride comfort and handling stability is a major challenge in active suspension design. This thesis investigates the development of novel active suspension systems for successful implementation of IWM technology in electric cars. Towards such aim, several active suspension methods based on robust H∞ control methods are developed to achieve enhanced suspension performance by overcoming the conflicting requirement between ride comfort, suspension deflection and road holding. A novel fault-tolerant H∞ controller based on friction compensation is in the presence of system parameter uncertainties, actuator faults, as well as actuator time delay and system friction is proposed. A friction observer-based Takagi-Sugeno (T-S) fuzzy H∞ controller is developed for active suspension with sprung mass variation and system friction. This method is validated experimentally on a quarter car test rig. The experimental results demonstrate the effectiveness of proposed control methods in improving vehicle ride performance and road holding capability under different road profiles. Quarter car suspension model with suspended shaft-less direct-drive motors has the potential to improve the road holding capability and ride performance. Based on the quarter car suspension with dynamic vibration absorber (DVA) model, a multi-objective parameter optimization for active suspension of IWM mounted electric vehicle based on genetic algorithm (GA) is proposed to suppress the sprung mass vibration, motor vibration, motor bearing wear as well as improving ride comfort, suspension deflection and road holding stability. Then a fault-tolerant fuzzy H∞ control design approach for active suspension of IWM driven electric vehicles in the presence of sprung mass variation, actuator faults and control input constraints is proposed. The T-S fuzzy suspension model is used to cope with the possible sprung mass variation. The output feedback control problem for active suspension system of IWM driven electric vehicles with actuator faults and time delay is further investigated. The suspended motor parameters and vehicle suspension parameters are optimized based on the particle swarm optimization. A robust output feedback H∞ controller is designed to guarantee the system’s asymptotic stability and simultaneously satisfying the performance constraints. The proposed output feedback controller reveals much better performance than previous work when different actuator thrust losses and time delay occurs. The road surface roughness is coupled with in-wheel switched reluctance motor air-gap eccentricity and the unbalanced residual vertical force. Coupling effects between road excitation and in wheel switched reluctance motor (SRM) on electric vehicle ride comfort are also analysed in this thesis. A hybrid control method including output feedback controller and SRM controller are designed to suppress SRM vibration and to prolong the SRM lifespan, while at the same time improving vehicle ride comfort. Then a state feedback H∞ controller combined with SRM controller is designed for in-wheel SRM driven electric vehicle with DVA structure to enhance vehicle and SRM performance. Simulation results demonstrate the effectiveness of DVA structure based active suspension system with proposed control method its ability to significantly improve the road holding capability and ride performance, as well as motor performance

RF Characterization of Self-Interference Cancellation Using Phase Modulation and Optical SideBand Filtering

Full-Duplex scheme transmitting and receiving signals simultaneously in the same frequency band can significantly improve the throughput and the spectrum efficiency, and is considered as a candidate technology for the fifth generation (5G) wireless communication. However, the high power transmitted signal will interfere with the in-band weak received signal, which is called as RF self-interference. It cannot be simply removed by a notch filter or a narrow bandpass filter because the same frequency band is used for both transmitter and receiver. An optical approach to implement RF self-interference cancellation is proposed. Based on the inherent out-of-phase property between the left and right sidebands of phase-modulated signal and optical sideband filtering, the RF self-interference cancellation is achieved by tuning the delay time and amplitude in the optical domain. The cancellation depth of the system was measured for different frequencies and bandwidths. The cancellation performance affected by the time delay deviation, the amplitude deviation and phase response is analyzed according to experimental results. It gives the direction for the improvement of system performance. Finally, the full-duplex communication by using the optical SIC approach was also investigated. Signal of interest is recovered and the constellation diagram was also shown

Photonic enabled RF self-interference cancellation for full-duplex communication

Photonic enabled RF self-interference cancellation for full-duplex communication by using phase modulation and optical sideband filtering is proposed. Based on the inherent out-of-phase property between the left and right sidebands of phasemodulated signal and optical sideband filtering, the RF self-interference cancellation is achieved by tuning the delay time and amplitude in the optical domain. The operational principle of the proposed scheme is theoretically analyzed and the feasibility is experimentally demonstrated. The optical sideband filtering for the phase modulated signals is measured and the RF self-interference cancellation at different carrier frequencies is studied. The results show a good performance of the proposed photonic scheme for RF self-interference cancellation. The full-duplex communication based on the photonic enabled RF self-interference cancellation is also investigated

Multidrug-resistant Pseudomonas aeruginosa is predisposed to lasR mutation through up-regulated activity of efflux pumps in non-cystic fibrosis bronchiectasis patients

BackgroundMultidrug-resistant (MDR) Pseudomonas aeruginosa is a frequent opportunistic pathogen that causes significant mortality in patients with non-cystic fibrosis bronchiectasis (NCFB). Although the quorum sensing (QS) system is a potential target for treatment, lasR mutants that present with a QS-deficient phenotype have been frequently reported among clinical P. aeruginosa isolates. We aimed to investigate whether antibiotic resistance would select for lasR mutants during chronic P. aeruginosa lung infection and determine the mechanism underlying the phenomenon.MethodsWe prospectively evaluated episodes of chronic P. aeruginosa lung infections in NCFB patients over a 2-year period at two centers of our institution. QS phenotypic assessments and whole-genome sequencing (WGS) of P. aeruginosa isolates were performed. Evolution experiments were conducted to confirm the emergence of lasR mutants in clinical MDR P. aeruginosa cultures.ResultsWe analyzed episodes of P. aeruginosa infection among 97 NCFB patients and found only prior carbapenem exposure independently predictive of the isolation of MDR P. aeruginosa strains. Compared with non-MDR isolates, MDR isolates presented significantly QS-deficient phenotypes, which could not be complemented by the exogenous addition of 3OC12-HSL. The paired isolates showed that their QS-phenotype deficiency occurred after MDR was developed. Whole-genome sequencing analysis revealed that lasR nonsynonymous mutations were significantly more frequent in MDR isolates, and positive correlations of mutation frequencies were observed between genes of lasR and negative-efflux-pump regulators (nalC and mexZ). The addition of the efflux pump inhibitor PAβN could not only promote QS phenotypes of these MDR isolates but also delay the early emergence of lasR mutants in evolution experiments.ConclusionsOur data indicated that MDR P. aeruginosa was predisposed to lasR mutation through the upregulated activity of efflux pumps. These findings suggest that anti-QS therapy combined with efflux pump inhibitors might be a potential strategy for NCFB patients in the challenge of MDR P. aeruginosa infections

Construction of a High-Density Linkage Map and QTL Fine Mapping for Growth- and Sex-Related Traits in Channel Catfish (Ictalurus punctatus)

A high-density genetic linkage map is of particular importance in the fine mapping for important economic traits and whole genome assembly in aquaculture species. The channel catfish (Ictalurus punctatus), a species native to North America, is one of the most important commercial freshwater fish in the world. Outside of the United States, China has become the major producer and consumer of channel catfish after experiencing rapid development in the past three decades. In this study, based on restriction site associated DNA sequencing (RAD-seq), a high-density genetic linkage map of channel catfish was constructed by using single nucleotide polymorphisms (SNPs) in a F1 family composed of 156 offspring and their two parental individuals. A total of 4,768 SNPs were assigned to 29 linkage groups (LGs), and the length of the linkage map reached 2,480.25 centiMorgans (cM) with an average distance of 0.55 cM between loci. Based on this genetic linkage map, 223 genomic scaffolds were anchored to the 29 LGs of channel catfish, and a total length of 704.66 Mb was assembled. Quantitative trait locus (QTL) mapping and genome-wide association analysis identified 10 QTLs of sex-related and six QTLs of growth-related traits at LG17 and LG28, respectively. Candidate genes associated with sex dimorphism, including spata2, spata5, sf3, zbtb38, and fox, were identified within QTL intervals on the LG17. A sex-linked marker with simple sequence repeats (SSR) in zbtb38 gene of the LG17 was validated for practical verification of sex in the channel catfish. Thus, the LG17 was considered as a sex-related LG. Potential growth-related genes were also identified, including important regulators such as megf9, npffr1, and gas1. In a word, we constructed the high-density genetic linkage map and developed the sex-linked marker in channel catfish, which are important genetic resources for future marker-assisted selection (MAS) of this economically important teleost

Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage

Recurrent liver cancer after surgery is often treated with radiotherapy, which induces liver damage. It has been documented that activation of the TGF-β and NF-κB signaling pathways plays important roles in irradiation-induced liver pathologies. However, the significance of mTOR signaling remains undefined after irradiation exposure. In the present study, we investigated the effects of inhibiting mTORC1 signaling on irradiated livers. Male C57BL/6J mice were acutely exposed to 8.0 Gy of X-ray total body irradiation and subsequently treated with rapamycin. The effects of rapamycin treatment on irradiated livers were examined at days 1, 3, and 7 after exposure. The results showed that 8.0 Gy of irradiation resulted in hepatocyte edema, hemorrhage, and sinusoidal congestion along with a decrease of ALB expression. Exposure of mice to irradiation significantly activated the mTORC1 signaling pathway determined by pS6 and p-mTOR expression via western blot and immunostaining. Transient inhibition of mTORC1 signaling by rapamycin treatment consistently accelerated liver recovery from irradiation, which was evidenced by decreasing sinusoidal congestion and increasing ALB expression after irradiation. The protective role of rapamycin on irradiated livers might be mediated by decreasing cellular apoptosis and increasing autophagy. These data suggest that transient inhibition of mTORC1 signaling by rapamycin protects livers against irradiation-induced damage

Two-step fabrication of nanoporous copper films with tunable morphology for SERS application

peer-reviewedIt is important to design and fabricate nanoporous metals (NPMs) with optimized microstructures for specific applications. In this contribution, nanoporous coppers (NPCs) with controllable thicknesses and pore sizes were fabricated via the combination of a co-sputtering of Cu/Ti with a subsequent dealloying process. The effect of dealloying time on porous morphology and the corresponding surface enhanced Raman scattering (SERS) behaviors were systematically investigated. Transmission electron microscopy (TEM) identified the presences of the gaps formed between ligaments and also the nanobumps on the nanoparticle-aggregated ligament surface, which were likely to contribute as the “hot spots” for electromagnetic enhancement. The optimal NPC film exhibited excellent SERS performance towards Rhodamine 6G (R6G) with a low limiting detection (10−9 M), along with good uniformity and reproducibility. The calculated enhancement factor of ca. 4.71 × 107 was over Au substrates and comparable to Ag systems, promising the proposed NPC as a cheap candidate for high-performance SERS substrate

Active Suspension Control of Electric Vehicle Driven by Switched Reluctance Motor Based on Vibration Absorbing Structure

Active suspension control for in-wheel switched reluctance motor (SRM) driven electric vehicle with dynamic vibration absorber (DVA) based on robust H control method is presented. The mounting of the electric drives on the wheels, known as in-wheel motor (IWM), results in an increase in the unsprung mass of the vehicle and a significant drop in the suspension ride performance and road holding stability. Structures with suspended shaftless direct drive motors have the potential to improve the road holding capability and ride performance. The quarter car active suspension model equipped with in-wheel SRM is established, in which the SRM stator serves as a dynamic vibration absorber. The in-wheel SRM is modelled using an analytical Fourier fitting method. The SRM airgap eccentricity is influenced by the road excitation and becomes time-varying such that a residual unbalanced radial force is induced. This is one of the major causes of SRM vibration. Current chopping control (CCC) and pulse width modulation control (PWM) are adapted to suppress motor vibration. Moreover, a robust H controller is developed for the active suspension with DVA to further enhance vehicle ride performance. A comparison of passive suspension with conventional SRM, passive suspension with DVA, active suspension with DVA on vehicle suspension and SRM dynamic responses are presented. Simulation results under bump road excitation and random road excitation demonstrate the effectiveness of DVA structure active suspension system with proposed control method in enhancing suspension and motor performance

A Diastereodivergent and Enantioselective Approach to syn- and anti-Diamines: Development of 2-Azatrienes for Cu-Catalyzed Reductive Couplings with Imines that Furnish Allylic Amines

We introduce a new reagent class, 2-azatrienes, as a platform for catalytic enantioselective synthesis of allylic amines. Herein, we demonstrate their promise by diasteredivergent and enantioselective synthesis of syn- and anti-1,2-diamines by Cu-bis(phosphine)-catalyzed reductive couplings with imines. With Ph-BPE, anti-diamines are obtained, and with the rarely utilized t-Bu-BDPP, syn-diamines are generated.<br /